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KMID : 0355420210450020087
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Journal of Korean Academy of Oral Health
2021 Volume.45 No. 2 p.87 ~ p.91
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Antibacterial effect of mouthwash containing CPC against dental caries caused bacteria
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Cho Won-Ho
Cho Ja-Won
Yoo Hyun-Jun
Shin Kyong-Hoon
Shjn Gi-Hae
Jeon Yeol-Mae
Lee Jong-Cheon
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Abstract
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Objectives: The purpose of this study was to evaluate and report the antibacterial efficacy in relation to oral disease-causing bacteria using a mouthwash containing 0.05% CPC in an in vitro test.
Methods: The sterilization test and susceptibility assay of mouthwash containing 0.05% CPC were investigated against Streptococcus mutans, Streptococcus sobrinus, and Lactobacillus acidophilus; Streptococcus sanguinis as oral bacteria related to dental caries; Enterococcus faecalis as apical periodontitis-related bacteria; and Actinomyces israelii, Aggregatibacter actinomycetemcomitans, Fusobacterium nucleatum, Prevotella intermedia, Prevotella nigrescence, Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, and Filifactor alocis as periodontal disease-related bacteria.
Results: In the sterilization test, most of the bacteria had more than 99.99% sterilizing power for all samples but compared to other bacteria, the sterilizing power of these samples was not successful for L. acidophilus and E. faecalis bacteria. When comparing the sterilization power between the samples, sample 3 (0.05% CPC+20% ethanol) was the strongest.
Conclusions: In the antimicrobial activity test, sample 3 inhibited growth at the lowest concentration overall.
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KEYWORD
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Cetylpyridinium chloride, Mouthwashes, Streptococcus mutans
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